First global data, from Rosetta Lung-02 in first-line NSCLC, tell a familiar story.
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Silevertinib efficacy comes close to firmonertinib’s, but toxicity is a new worry.
The group’s first pivotal readout, in second-line pancreatic cancer, is coming.
A trial of one KRAS G12D inhibitor is halted early, while that of another sees tox troubles.
The Kandlelit-013 trial of calderasib plus Keytruda in adjuvant NSCLC will start in April.
The Japanese group will soon start a trial of its Reblozyl rival in first-line MDS.
Cullgen’s oncology portfolio features TRK, GSPT1 and CDK2 degraders.
But now it must show that varseta-M can move into a registrational trial.
