AACR 2025 – Merck's head and neck headscratcher
Keynote-689 delivers a win in all-comers, but how did PD-L1-negatives do?
Keynote-689 delivers a win in all-comers, but how did PD-L1-negatives do?
But half the responses with the KRAS G12D inhibitor zoldonrasib are unconfirmed.
But sasanlimab's use looks set to remain narrow.
The curtain lifts on Veritac-2, rusfertide, and another double plenary for Astra.
Novel targets including Ly6E and LRRC15 feature alongside more popular mechanisms.
At least 15 dual-payload ADCs will be discussed.
In first-line SCLC BNT327 looks better than Tecentriq, but data will need to be replicated outside China.
On key measures Keynote-D77 shows subcutaneous delivery to be the equal of IV.
Ikena, Senti and others look to clinical presentations at AACR.