Skip to main content
x

CureVac goes out with a whimper

CureVac agreeing to an all-stock acquisition by BioNTech is an ignominious end for a company that had once claimed to be able to rival Moderna in mRNA expertise. The transaction, announced on Thursday, values Curevac shares at just $5.46, 95% below their 2021 peak towards the end of the Covid pandemic. Still, at least the deal allows CureVac holders to enjoy any subsequent accretion in BioNTech shares, while drawing a line under disappointments that last year resulted in a 30% headcount reduction, and licensing of Covid and influenza work to GSK. CureVac is effectively an oncology-focused company, with a small portfolio of cancer immunotherapies, and that clearly fits with BioNTech's presence in personalised neoantigen and fixed antigen therapeutics. But there might be a more prosaic reason for the deal: CureVac and BioNTech have been locked in legal proceedings over the latter's Covid vaccine Comirnaty, which CureVac claims infringes its patents, and just last month the European Patent Office confirmed the validity of CureVac’s European patent. Buying CureVac without any financial outlay allows BioNTech to avoid the nuisance of further litigation.

 

CureVac's work in oncology

ProjectMechanismStatus
CVGBMmRNA immunotherapeutic against 8 antigensPh1 in brain cancer
CVHNLCmRNA immunotherapeutic from myNEO collaborationPreclinical
UnnamedMD Anderson collaborationPreclinical
CV8102TLR 7/8 RIG-1 agonistPh1 status unknown
BI 1361849/ CV9202mRNA immunotherapeutic against 6 antigensDiscontinued in ph1
CV9103/ CV9104mRNA immunotherapeuticDiscontinued in ph1/2

Source: OncologyPipeline.

Tags