 
German Merck makes SpringWorks holders squirm
 
SpringWorks holders haven't had it easy since their company was confirmed to be in "advanced discussions" over a takeover bid from Merck KGaA last month. Weeks of silence have followed, suggesting that the companies can't agree on a price, and now investors have another worry: Merck has instead done a deal with Abbisko on the latter's CSF-1R inhibitor pimicotinib. Still, a more positive read is that Merck has been preoccupied with pimicotinib, and it's now free to turn to the bigger matter of a $4bn SpringWorks acquisition. The Abbisko deal follows a December 2023 tie-up under which Merck paid $70m for Asia rights to pimicotinib in the niche condition tenosynovial giant cell tumour. Pimicotinib could have an edge over Ono's Deciphera-originated and now US-approved Romvimza, judging by data from the phase 3 Manuever study, a win that on Friday persuaded Merck to take up an option over global pimicotinib rights for $85m. On 6 March Evercore ISI's Cory Kasimov wrote that a SpringWorks takeover was still on, citing the lack of a statement from Merck saying it wasn't, and SpringWorks' cancellation of an investor meeting; perhaps new bidders have entered, but there's been no update since.
Will they, won’t they? Merck KGaA’s SpringWorks timeline
| Date | Comment | 
|---|---|
| 10 Feb 2025 | Merck KGaA confirms press reports, stating it’s in “advanced discussions” with SpringWorks | 
| 11 Feb 2025 | SpringWorks gets it second US approval: Gomekli, for adult & paediatric neurofibromatosis type 1-associated plexiform neurofibromas | 
| 6 Mar 2025 | Merck KGaA annual report reiterates the advanced discussions, and company says it’s focused on clear-cut, low-risk deals | 
| 11 Mar 2025 | SpringWorks due to present at the Barclays healthcare conference, but cancels | 
| 28 Mar 2025 | Merck KGaA pays $85m for global rights to Abbisko’s pimicotinib | 
Source: company statements.
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