First global data, from Rosetta Lung-02 in first-line NSCLC, tell a familiar story.
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Silevertinib efficacy comes close to firmonertinib’s, but toxicity is a new worry.
Data with the T-cell engager ASP2138 look lukewarm, but could improve with combos.
And Vironexis’s second gene therapy-encoded T-cell engager will soon go clinical.
The group toplines a phase 2 win with Alphamedix.
The biggest Q3 agreement was AbbVie’s $700m swoop for Glenmark's trispecific T-cell engager.
A phase 3 trial of Hernexeos in adjuvant HER2m NSCLC is planned.
And Treeline and HengRui also get in on the pan-RAS act.