ASH 2025 – BeOne pulls away from Nurix
On efficacy, at least, BeOne’s BTK degrader shows an edge.
On efficacy, at least, BeOne’s BTK degrader shows an edge.
It’s less about being fast, more about producing a better product.
Of 15 treatment-emergent adverse events, only one was deemed related to therapy.
Relapsed data are uncompetitive, but the front-line PACC-mutant space offers hope.
Readout of the Preserve-003 trial in post-PD-(L)1 NSCLC is due in December.
The project has priority review, but deaths could raise eyebrows.
An in vivo Car-T produced a 100% response rate – in three patients.
Rival BTK degraders face off, as do bispecific Cars and T-cell engagers.
Data will be presented on Kura’s Komzifti and Syndax’s Revuforj in first-line AML.