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  1. AstraZeneca doubles down on GPC3

    … which had yielded phase 1 safety and biomarker data at ESMO 2023. The company didn’t give a reason for its …

    - 06/16/2025 - 13:14

  2. Mersana shows that B7-H4 expression matters

    … basis of a 29% ORR among 28 TNBC patients, reported at ESMO 2023 . However, while this Chinese trial enrolled …

    - 06/30/2025 - 12:24

  3. Triple meeting 2024 – Zai Lab impresses in small cell

    … Presentation venue Triple meeting 2024 ESMO 2023 ASCO 2024 ORR 74% (14/19)* 40% …

    - 10/29/2024 - 13:27

  4. Merck and Daiichi look beyond small cell with ifinatamab

    … Safety, antitumour activity Data at WCLC & ESMO 2023: ORR 52% in SCLC; 21% in ESCC; 25% in mCRPC; 31% …

    - 10/24/2024 - 13:51

  5. No easy ride for Turnstone

    … TIL BioNTech BNT221 (ex Neon) disappointed at ESMO 2023 Personalised neoantigen-specific TIL …

    - 10/15/2024 - 14:25

  6. Triple meeting 2024 – can Revolution succeed where others stumbled?

    … efforts to hit this target have so far fallen short: at ESMO 2023, Jiangsu HengRui’s inhibitor HRS-4642 produced …

    - 10/25/2024 - 14:51

  7. KRAS strikes back

    … Jiangsu Hengrui’s inhibitor HRS-4642 disappointing at ESMO 2023, and Astellas’s degrader ASP3082 underwhelming …

    - 10/01/2024 - 14:30

  8. Dato sees double survival trouble

    … all-comers was 12.9mth vs 11.8mth (HR=0.94, p=0.530); **at ESMO 2023 interim OS was described as numerically favourable …

    - 09/24/2024 - 15:07

  9. ESMO 2024 – Torl challenges BioNTech in Claudin6

    … of BNT211 was deemed to be toxic by the discussant at ESMO 2023 , Centre Léon Bérard’s Dr Philippe Cassier. …

    - 09/17/2024 - 12:26

  10. ESMO 2024 – Astra’s B7-H4 effort underwhelms

    … inhibitor 6 Ph1 China study in solid tumours ESMO 2023: 29% ORR in 28 TNBC pts XMT-1660 Mersana …

    - 09/15/2024 - 08:35