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  1. Dato sees double survival trouble

    … all-comers was 12.9mth vs 11.8mth (HR=0.94, p=0.530); **at ESMO 2023 interim OS was described as numerically favourable …

    - 09/24/2024 - 15:07

  2. ESMO 2024 – Torl challenges BioNTech in Claudin6

    … of BNT211 was deemed to be toxic by the discussant at ESMO 2023 , Centre Léon Bérard’s Dr Philippe Cassier. …

    - 09/17/2024 - 12:26

  3. ESMO 2024 – Astra’s B7-H4 effort underwhelms

    … inhibitor 6 Ph1 China study in solid tumours ESMO 2023: 29% ORR in 28 TNBC pts XMT-1660 Mersana …

    - 09/15/2024 - 08:35

  4. ESMO 2024 preview – Astellas’s KRAS degrader disappoints

    … KRAS G12D inhibitor When presented ESMO 2024 ESMO 2023 Study Ph1 global study Ph1 …

    - 10/04/2024 - 15:06

  5. Amgen packs up in Claudin6

    … Car-T Ph1 in solid tumours (NCT04503278) Data at ESMO 2023; ph2 in testicular germ cell tumours to start 2024 …

    - 05/31/2025 - 23:59

  6. IO Biotech looks for an interim injection

    … & UBC + Keytruda (uncontrolled) Preliminary data at ESMO 2023; more data expected autumn 2024 PN-E40 …

    - 06/27/2024 - 20:11

  7. ASCO 2024 – full Evoke-01 result adds to Gilead’s Trodelvy problems

    … and a secondary endpoint in Evoke-01. Source: ESMO 2023 & ASCO 2024. Conferences …

    - 06/01/2024 - 22:08

  8. EHA 2024 preview – Novartis doubles up

    … Anti-CD123 NK cell engager S146 Had data at ESMO 2023 Roche Englumafusp alfa …

    - 05/20/2024 - 18:11

  9. J&J speeds into new bladder cancer trial

    … pts with FGFR alterations Ph1 data at ESMO 2023: 87% CR rate in 15 pts in cohort 3 (BCG-naive) … BCG-experienced pts with FGFR mutations Data at ESMO 2023: 72% reduction in risk of recurrence/death in 73 … Ph2 Sunrise-1 in high-risk BCG-unresponsive pts, data at ESMO 2023: 77% CR rate in 30 pts Source: …

    - 04/23/2024 - 13:00

  10. BioNTech has some cancer convincing to do

    … Car-T N/A Ph1/2 in solid tumours Data at ESMO 2023 showed promising efficacy, but with tox …

    - 03/21/2024 - 13:20