ESMO 2024 – Regeneron's fianlimab do-over
Response rates in a key group shrink from 62% to 39% as the company blames a “clerical error”.
Response rates in a key group shrink from 62% to 39% as the company blames a “clerical error”.
Meanwhile, recent updates hint at more issues in the group’s pipeline of bispecific MAbs.
Following its odronextamab knockback, Regeneron now faces a delay to linvoseltamab.
But the company hasn’t given details, and used a historical control rather than the study’s own control arm.
Meanwhile, the RayzeBio-originated RYZ101 is back in Action.
Roche curbs its TIGIT push, while a co-stimulation crunch could be bad news for Regeneron.
Merck and Daiichi’s first ADC attempt is knocked back, while Geron gets its inaugural approval.
The EU recommendation for odronextamab comes after a US rejection in March.
A second Lilly Nectin-4 ADC features among the latest phase 1 initiations.