ASCO 2025 preview – KRAS challengers assemble
Lilly, Merck & Co and Verastem could take on Amgen, Bristol and Revolution.
Lilly, Merck & Co and Verastem could take on Amgen, Bristol and Revolution.
The company deprioritises its lead project, naporafenib, shifting to two Joyo-originated assets.
The group’s latest update focused on new data with the KRAS G12C inhibitor elironrasib.
But half the responses with the KRAS G12D inhibitor zoldonrasib are unconfirmed.
Skyscraper-01 stars at AACR's upcoming clinical trial plenary.
Amid a KRAS data dump, a doublet of RMC-6236 and RMC-6291 was a highlight.
RMC-9805 looks more efficacious, and less toxic, than Astellas’s G12D degrader in pancreatic cancer.
The group will present the first clinical data on its KRAS G12D-selective project RMC-9805.