AACR 2025 – Revolution shows lung promise
But half the responses with the KRAS G12D inhibitor zoldonrasib are unconfirmed.
But half the responses with the KRAS G12D inhibitor zoldonrasib are unconfirmed.
Skyscraper-01 stars at AACR's upcoming clinical trial plenary.
Amid a KRAS data dump, a doublet of RMC-6236 and RMC-6291 was a highlight.
RMC-9805 looks more efficacious, and less toxic, than Astellas’s G12D degrader in pancreatic cancer.
The group will present the first clinical data on its KRAS G12D-selective project RMC-9805.
Despite seeing dose-limiting toxicities, the group is going higher with its KRAS G12D project.
So far ASP3082 looks no better than Jiangsu HengRui’s straight KRAS G12D inhibitor.
The group reaffirms pancreatic cancer promise with RMC-6236, but has it found the best dose?