ESMO 2025 – Boehringer and Bayer eye the front line
Boehringer’s Hernexeos and Bayer’s sevabertinib look similar in first-line HER2-mutant NSCLC.
Boehringer’s Hernexeos and Bayer’s sevabertinib look similar in first-line HER2-mutant NSCLC.
And Vironexis’s second gene therapy-encoded T-cell engager will soon go clinical.
A phase 3 trial of Hernexeos in adjuvant HER2m NSCLC is planned.
The ESMO presidential session will feature data from Destiny-Breast05 and 11.
Meanwhile, Astra, Merck and Novartis look for new Enhertu, Keytruda and Pluvicto additions.
The company, apparently unbothered by Enhertu, is starting a new HER2 x HER2 phase 3.
Enhertu plus Perjeta shows a convincing progression-free survival benefit over a Perjeta triplet.