ASH 2024 – J&J mounts its first-line menin challenge
The group presents data with bleximenib plus chemo, but looks behind Kura’s contender.
The group presents data with bleximenib plus chemo, but looks behind Kura’s contender.
JNJ-89853413 is disclosed as the lead in the two companies' 2020 alliance.
Syndax scored the first menin approval, but Kura is first with a licensing deal.
Response rates in relapsed NPM1-mutant AML look slightly worse than before, but QTc prolongation could be the real worry.
Kura will see more combo data, while a new contender from Sumitomo emerges.
The group reports responses with its CD123-targeting ADC, but cash is running short.
The depressed company could use Mylotarg as a stepping stone in AML.