Revolution could have a first-line pancreatic balancing act
Efficacy looks better with daraxonrasib plus chemo versus monotherapy, but toxicity looms.
Efficacy looks better with daraxonrasib plus chemo versus monotherapy, but toxicity looms.
Pivotal data set the stage for slightly delayed US accelerated approval filing.
So far the data, with a Car-T Legend licensed to Novartis, lag antibody approaches.
Global data are in the same ballpark as Chinese results presented earlier this year.
But results come from a curated dataset, with no in-trial comparator.
A common mutation comes into play for PRMT5 inhibition.
Investors now have more reasons to doubt Harmoni's ability to back US approval.
Early data with IDE849 look better those with Zai’s zocilurtatug pelitecan.
Tolerability could decide first-line therapy in EGFRm disease.