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Argenx’s efforts to Advance fall flat

Failure of a subcutaneous formulation of Vyvgart raises questions about the drug’s future in primary immune thrombocytopenia and beyond.

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TROP2 gets more crowded

The latest first-in-human entrants include an anti-TROP2 ADC from Jiangsu Hansoh and a mystery bispecific from Johnson & Johnson.

A reprieve for Blenrep?

Against the odds GSK’s Dreamm-7 study yields a positive survival readout.

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ASH 2023 preview – Darzalex gets a first-line boost from Perseus

But, with the end in sight for the CD38 blockbuster, will Johnson & Johnson buy into Genmab’s next-gen project?

A curate’s egg for MorphoSys

Pelabresib’s Manifest-2 trial yields mixed data, but the bad part could render the whole unpalatable.

Merck goes pivotal with acquired assets

A prostate cancer project licensed from Orion enters phase 3, while pivotal trials are expanded with assets originated at Kelun and Arqule.

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