ApexOnco Front Page Recent articles 20 March 2026 Like Lilly, Novartis bets against mutation specificity The Swiss group shells out $2bn for Synnovation’s mutation-selective PI3Kα inhibitor. 20 March 2026 AACR 2026 – one more shot for integrins A unique VEGF trispecific and mRNA-based T-cell engager will also be featured at the congress. 8 December 2023 A triplet of Keytruda failures Merck sees clinical setbacks in Keylynk-008, Leap-001 and Keyvibe-002. 6 December 2023 SABCS 2023 – SERDs square off in combinations Arvinas’s SERD appears to edge out Olema’s, but what’s the best CDK4/6 inhibitor for a phase 3 combination? 5 December 2023 Crispr abandons first-generation Car-T projects The company hopes that new edits could solve the relapse problem with allogeneic Car-Ts. 5 December 2023 Roche seeks alpha to defeat Novartis With inavolisib’s pivotal front-line win Roche reckons it can knock out Novartis’s Piqray. 4 December 2023 Lilly makes steady progress in non-covalent BTK inhibition Jaypirca secures a CLL label, though plans to dominate will be tempered by this market’s fast-changing nature. 4 December 2023 ESMO Asia 2023 – deaths raise doubts about Merus’s Rybrevant challenger Merus still hopes for a future for MCLA-129, but the doors are closing. Load More Recent Quick take Most Popular