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Is this the end for MacroGenics’ vobra-duo?

The company stops dosing in the troubled Tamarack trial, and is going quiet until ESMO.

BioNTech claims a FixVac win

But the company hasn’t given details, and used a historical control rather than the study’s own control arm.

Bristol cuts its BCMA losses

Meanwhile, the RayzeBio-originated RYZ101 is back in Action.

Crunch time for Bristol’s TIGIT bet

Now in Bristol’s hands, BMS-986442 is set to deliver its first clinical data.

Aegean in the clear

But Imfinzi's precise setting is uncertain, and big problems loom for companies pursuing similar trials.

Roche’s Skyscraper looks on shaky foundations

Roche curbs its TIGIT push, while a co-stimulation crunch could be bad news for Regeneron.

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