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A new dawn for tovorafenib

The FDA's tough stance notwithstanding, Ojemda gets an accelerated green light.

Mythic goes back to basics

More efficient internalisation and release – not bystander activity – are the focus for this private ADC player.

How hot are antibody-drug conjugates?

An analysis of OncologyPipeline shows that $144bn has been pledged for ADCs since the start of 2022.

GenFleet bids to join the colorectal KRAS crowd

Competitors have given up on monotherapies in this use, but GenFleet wants to buck the trend.

Volastra vies for the next big synthetic lethality target

The group reckons big pharma is eyeing KIF18A inhibition, but for now there are just a handful of players.

CCR8 expectations

Blockade of CCR8 has quietly emerged as a hot oncology target, especially for anti-PD-(L)1 MAb combinations.

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