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AstraZeneca doubles down on GPC3

The company takes its T-cell engager into the clinic, just as Roche and Sanofi exit.

Pfizer drops its B7-H4 conjugate

Felmetatug vedotin’s exit could be bad news for Mersana.

FDA red and green lights: January 2025

AstraZeneca bags three of the month’s four oncology approvals.

Pivotal study designs revealed

Keenly awaited trials of ficerafusp alfa, Trodelvy and divarasib materialise.

Cargo can't replicate firi-cel's academic success

Firce-1 is scrapped after showing dismal response rates and patient deaths.

Zentalis doubles down on Wee1

But the new focus on a predictive biomarker could cut the market in half.

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