The CD70-targeting CTX131 heads for the scrapheap.
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Bezuclastinib plus Sutent could become standard of care in second-line GIST.
The company’s long-delayed pivotal trial is hit by a stronger-than-expected placebo performance.
The new developer will focus on the crowded KRAS space and PI3Kα/AKT inhibition, which has been hit by toxicity issues.
AstraZeneca celebrates success in the Echo trial in mantle cell lymphoma, but watch out for BeiGene.
The $1bn price tag for the preclinical Mariana Oncology shows that competition for assets in this space is fierce.
Hopes are high for petosemtamab head and neck data at ASCO, but what does a win look like?
Daiichi and AstraZeneca claim another breast cancer success, and further evidence of the ADC’s activity in very low HER2 expression.