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More bad vibes kill off Merck’s TIGIT and Lag3

Merck ditches vibostolimab and favezelimab following huge pivotal programmes.

Bicycle has a wobble

Zelenectide looks uncompetitive versus Padcev in bladder cancer, while elsewhere a biomarker strategy beckons.

SABCS 2024 – Lilly's PI3Kα push is no longer mutation-specific

Lilly sheds more light on its second PI3Kα take, as Relay's combo data improve.

Another pan-KRAS project enters the clinic

Quanta now has a “G12V-preferring” multi-KRAS asset on its clinical roster.

Elevation brings Synaffix on board in HER3

But the group is going up against the likes of Merck/Daiichi, Bristol Myers Squibb and BioNTech.

ASH 2024 movers – moments of reckoning for menin and BTK

Menin, BTK and a Car-T skirmish featured over the ASH weekend.

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