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FibroGen hopes to buck its pamrevlumab trend

Two pancreatic cancer trials will read out this quarter, but after a string of failures with the project they look like a long shot.

Familiar targets with a twist

First-in-human study initiations feature variations on well-trodden targets, plus a minor hiccup for OncoC4.

AACR 2024 – a first look at Astra’s ATM inhibitor

One of the first human datasets concerning an ATM inhibitor shows glioblastoma’s intractability.

AACR 2024 – Transgene gets a “vaccine” boost

Early data with the group’s personalised project intrigue, but Transgene has a long road ahead.

AACR 2024 – Medicenna looks for a cytokine renaissance

After numerous IL-2 failures there are glimmers of hope for the group’s contender, MDNA11.

AACR 2024 – Vincerx overreaches

The company's comparison of its ADCs to Enhertu seems farfetched.

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