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FDA critics barely lay a glove on Geron

Imetelstat appears headed for approval after its US adcom turns into a damp squib.

Multiple myeloma Car-Ts face a US grilling

The FDA highlights high death rates and questions overall survival for Carvykti and Abecma.

Seven problems for Geron

Brutal FDA briefing documents raise questions about the approvability of imetelstat for myelodysplastic syndromes.

Early tests approach for Vincerx’s conjugate revolution

The company reckons its tech could solve problems with current ADCs, but the market isn’t giving it much credit yet.

Deals mask CytomX’s fundamental problem

Another disappointment raises fresh doubts about CytomX’s extensively partnered masked therapeutics.

Adcetris gives Pfizer its first post-Seagen surprise

The Echelon-3 study seemed doomed, but it just read out positively for overall survival.

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