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Fresh questions over DLL3

Five years after AbbVie pulled the plug on rova-T, DLL3 comes under the spotlight again.

CD19 is worth $700m to Merck

Merck turns to China for a molecule against one of biopharma’s most extensively studied antigens.

Agenus looks to new deals and an ex-US path

But there are no hard facts, and a Ligand obligation clouds future licensing economics.

TIGIT blows up in a trial that always looked risky

Keyvibe-008 is halted for futility, an outcome that might have been foreseen in 2022.

The month ahead: August’s remaining events

Following its odronextamab knockback, Regeneron now faces a delay to linvoseltamab.

Blood cancer gene therapies enter the clinic

First-in-human trial initiations feature Interius, Umoja and Vironexis.

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