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SABCS 2023 – SERDs square off in combinations

Arvinas’s SERD appears to edge out Olema’s, but what’s the best CDK4/6 inhibitor for a phase 3 combination?

Car-T cells attacking cancer cell
Crispr abandons first-generation Car-T projects

The company hopes that new edits could solve the relapse problem with allogeneic Car-Ts.

Roche seeks alpha to defeat Novartis

With inavolisib’s pivotal front-line win Roche reckons it can knock out Novartis’s Piqray.

ESMO Asia 2023 – deaths raise doubts about Merus’s Rybrevant challenger

Merus still hopes for a future for MCLA-129, but the doors are closing.

Lilly makes steady progress in non-covalent BTK inhibition

Jaypirca secures a CLL label, though plans to dominate will be tempered by this market’s fast-changing nature.

AbbVie banishes the ghost of Stemcentrx

Yet another ADC deal sees AbbVie buy ImmunoGen, ending a 40-year rollercoaster ride with a 100% overnight premium.

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