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Xencor could face second challenge from former partner

J&J's new anti-ENPP3 ADC appears – and then disappears – from a clinical study listing.

Another false dawn for p53

Boehringer discontinues brigimadlin while others continue to struggle.

BridgeBio enters the pan-KRAS game

Meanwhile, Akeso challenges Moderna and BioNTech with an mRNA neoantigen play.

Crispr’s Car-T crunch time

The group could soon provide clarity on CTX112’s regulatory path.

MAIA throws more money at ateganosine

The THIO-104 study listing is live, along with questions about funding the trial.

A second shot at PARP1 from Eikon

The private US biotech features among recent first-in-human study entrants, with another PARP1-selective molecule.

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