Roche pushes a novel myeloma target
The company will be the first to take a FcRH5-targeting project into phase 3.
The company will be the first to take a FcRH5-targeting project into phase 3.
Like Orserdu, giredestrant works in all-comers in an ESR1m-enriched trial.
Big pharma interest remains, but the mood is fast turning gloomy.
After menin, the company tries again with farnesyl transferase.
Efficacy looks better with daraxonrasib plus chemo versus monotherapy, but toxicity looms.
Pivotal data set the stage for slightly delayed US accelerated approval filing.
So far the data, with a Car-T Legend licensed to Novartis, lag antibody approaches.