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ESMO 2024 – J&J eyes Rybrevant colorectal expansion

Early data on Rybrevant plus chemo have spurred a quick leap into pivotal trials.

ESMO 2024 – Opdualag comes under fire

Relativity-104 is revealed as a failure, and the phase 3 it just spawned could fail too.

ESMO 2024 – iTeos TIGIT meets its efficacy criteria

But the Galaxies Lung-201 trial features notable omissions, plus toxicity.

ESMO 2024 – Nuvalent looks beyond its late-line Alkove

Efficacy with the group’s next-gen ALK and ROS1 inhibitors holds up, and first-line use could beckon.

ESMO 2024 – MediLink impresses in small-cell lung cancer

The group’s B7-H3 ADC looks competitive versus rival projects from Merck/Daiichi and GSK/Hansoh.

ESMO 2024 – NiKang’s case for a better Welireg

The company’s HIF-2α inhibitor impresses on efficacy, but its long half life raises eyebrows.

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