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Cell cycle niche seeks clinical validation

Several companies have followed Pfizer into CDK2 inhibitor development, but the jury is out on this field’s promise.

J&J deal cements Ambrx’s transformation

Ambrx’s PSMA-targeting ADC generated puzzling data at ESMO, but J&J has seen enough to launch a premium-priced buyout.

Merck’s latest move is in bispecifics

A $680m swoop for Harpoon will fill a hole in Merck’s pipeline.

Two allogeneic cell therapy switches in a day

Allogene joins Adicet in going back to the drawing board and scrapping trials in late-line aggressive lymphoma.

Merck KGaA takes a punt on Inspirna’s novel approach

The German group hopes to expand its colorectal cancer offering, taking on the only SLC6A8 inhibitor in development.

Adicet pivots

After disappointments in aggressive lymphomas Adicet focuses ADI-001 development on mantle cell lymphoma and goes into lupus.

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