SGN-CEACAM5C carries the same antibody as the discontinued tusamitamab ravtansine.

Padcev has eaten into bladder expectations, while a Tukysa trial has also gone.

An actinium-based backup and Werner helicase inhibitor are notable absences.

But the Astra/Daiichi ADC stumbles in lung cancer.

First-in-human listings bring a bispecific and yet another in vivo Car-T.

The company is starting four new pivotal trials this year.