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ESMO 2024 – Keytruda/Lenvima leap... up to a point

Leap-012 delivers a technical win, but filing might hinge on overall survival and a call on toxicity.

ESMO 2024 – changing FDA stance could haunt Astra’s Niagara win

Niagara looks sound, but how much benefit did Imfinzi contribute to each of its two settings?

ESMO 2024 – Nuvalent looks beyond its late-line Alkove

Efficacy with the group’s next-gen ALK and ROS1 inhibitors holds up, and first-line use could beckon.

ESMO 2024 – NiKang’s case for a better Welireg

The company’s HIF-2α inhibitor impresses on efficacy, but its long half life raises eyebrows.

ESMO 2024 – Opdualag comes under fire

Relativity-104 is revealed as a failure, and the phase 3 it just spawned could fail too.

ESMO 2024 – Incyte tries again in anal cancer

Having failed to get Zynyz approved in the second-line setting the group has the front line in its sights.

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