October's US approvals included Scemblix, Vyloy and Itovebi, while Lumakras was delayed.

The group goes after a KRAS-related target on which Boehringer recently gave up.

Conferences ramp up, and ASH abstracts near.

Pelabresib is delayed, and Novartis writes off $800m of the €2.7bn purchase.

RMC-9805 looks more efficacious, and less toxic, than Astellas’s G12D degrader in pancreatic cancer.

There’s little to distinguish the two HIF2α inhibitors in kidney cancer.