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  1. Nuvation gets in before Nuvalent

    … has 11 to 20-fold selectivity for ROS1 over TRK. In an ESMO 2024 poster Nuvalent put this at a more conservative …

    - 06/12/2025 - 15:10

  2. ASCO 2025 – BioNTech’s latest Claudin6 effort falls short

    … *another 4 responses were unconfirmed. Source: ASCO 2025 & ESMO 2024.   Complicating the cross-trial comparison …

    - 06/01/2025 - 21:08

  3. Another TIGIT bites the dust

    … + Jemperli, vs Jemperli ORR ORR improvement at ESMO 2024; no meaningful improvement in PFS, as per May 2025 …

    - 05/14/2025 - 15:34

  4. Qilu nabs a new B7-H3 contender

    … China ph3s in SCLC & head & neck Looked competitive at ESMO 2024 in SCLC MHB088C Minghui/ Qilu Topo1 …

    - 05/13/2025 - 16:22

  5. AACR 2025 preview – distressed biotechs seek redemption

    … Ph1 in KRAS G12D-resistant NSCLC Had data at ESMO 2024 IK-595 MEK-RAF molecular glue Ikena …

    - 03/28/2025 - 08:55

  6. Acrivon CHKs itself

    … 2 trial of ACR-368   Mar 2025 update ESMO 2024 Patient subgroup BM+ BM- …

    - 03/27/2025 - 13:27

  7. SGO 2025 – Genmab’s advantage looks Profound

    … cohort B1 results   SGO 2025 ESMO 2024 Cutoff date 15 Jan 2025 28 Jul …

    - 03/20/2025 - 16:08

  8. Merck and Sanofi sound the alarm for ILT inhibition

    … of BND-22 had posted “encouraging results”. However, an ESMO 2024 presentation suggests otherwise and there must now …

    - 03/07/2025 - 18:26

  9. GSK and Hansoh press on despite Pfizer’s exit

    … AstraZeneca ADC Ph1/2 underwhelmed at ESMO 2024, with ORR 25% in ≥25% expressers …

    - 03/06/2025 - 13:28

  10. Bristol exits KRAS G12D

    … Astellas Degrader Lacklustre ph1 data at ESMO 2024; proof-of-concept judgement due in H1 2025 …

    - 03/06/2025 - 13:30