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  1. ASCO-GI – Astellas focuses on a degrader-chemo combo

    … which initially reported disappointing results at ESMO 2024 from the same phase 1 trial.   Phase 1 …

    - 01/13/2026 - 13:49

  2. HengRui goes pivotal in KRAS G12D

    … stages. That project initially failed to impress at ESMO 2024, but produced more promising efficacy results in …

    - 12/02/2025 - 13:31

  3. Nuvalent presses ahead in ALK

    … ALKi Post Lorbrena Phase 1 part (ESMO 2024) Patients NA 103 17 85 …

    - 11/18/2025 - 14:23

  4. Gastrointestinal is next for pumitamig

    … same setting, ivonescimab plus chemo produced an 82% ORR at ESMO 2024. Meanwhile, the Rosetta Gastric-204 trial will …

    - 11/11/2025 - 14:36

  5. Triple meeting 2025 – Astellas touts a degrader turnaround

    … At ESMO 2024, Astellas’s KRAS G12D degrader ASP3082 looked …

    - 11/03/2025 - 16:56

  6. ESMO 2025 – J&J brings a new Rybrevant use into the fold

    … After Johnson & Johnson’s Rybrevant intrigued at ESMO 2024 in colorectal cancer the company now has its eye …

    - 10/20/2025 - 12:52

  7. Incyte goes pivotal in CDK2

    … & ovarian cancers +/- Ibrance, +/- Faslodex; data at ESMO 2024 + atirmociclib (CDK4i) in breast cancer: 28% ORR …

    - 10/16/2025 - 12:33

  8. J&J goes straight into phase 3 in prostate

    … an anti-Steap1 T-cell engager. Still, data presented at ESMO 2024 showed efficacy broadly in line with ARX517 and …

    - 09/16/2025 - 14:56

  9. J&J’s bladder hope gets its first approval

    … cystectomy + cetrelimab, vs cetrelimab Data at ESMO 2024: pCR 42% with TAR-200 + cetrelimab, vs 23% with …

    - 09/12/2025 - 10:17

  10. Nuvation gets in before Nuvalent

    … has 11 to 20-fold selectivity for ROS1 over TRK. In an ESMO 2024 poster Nuvalent put this at a more conservative …

    - 06/16/2025 - 13:48