ESMO 2025 – Padcev plus Keytruda sets the perioperative bar
Keynote-905 finds a 50% reduction in the risk of death in (neo)adjuvant muscle-invasive bladder cancer.
Keynote-905 finds a 50% reduction in the risk of death in (neo)adjuvant muscle-invasive bladder cancer.
Data with the T-cell engager ASP2138 look lukewarm, but could improve with combos.
Meanwhile, Astra, Merck and Novartis look for new Enhertu, Keytruda and Pluvicto additions.
Astellas’s pan-KRAS degrader joins the company’s two clinical-stage G12D degraders.
But half the responses with the KRAS G12D inhibitor zoldonrasib are unconfirmed.
The company buys Belgium’s EsoBiotec for $425m.