ESMO 2025 – Boehringer and Bayer eye the front line
Boehringer’s Hernexeos and Bayer’s sevabertinib look similar in first-line HER2-mutant NSCLC.
Boehringer’s Hernexeos and Bayer’s sevabertinib look similar in first-line HER2-mutant NSCLC.
The company has seen a PFS and OS benefit in the phase 3 Majestec-3 trial.
But more detail is awaited, especially on toxicity.
The ESMO regular abstract lift reveals first human datasets for several projects.
Data with the T-cell engager ASP2138 look lukewarm, but could improve with combos.
The group toplines a phase 2 win with Alphamedix.
Datroway succeeds on PFS and OS in Tropion-Breast02, and an ESMO showdown beckons.