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Three mystery phase 1 entrants

Bristol, AbbVie and Jiangsu HengRui move to enter clinical trials with undisclosed mechanisms of action.

Lumakras withdrawal seems unlikely... for now

But a US adcom slams Amgen’s oversight of Codebreak-200, as the group’s KRAS rival Mirati surges on takeover talk.

Triple data take Nuvalent's market cap above $3bn

After touting NVL-655 as being active in patients resistant to a third-generation ALK inhibitor, Nuvalent now has clinical data to back this up.

Triple meeting 2023 preview – firsts for Amgen and Novartis

But Repare and Black Diamond still have rebuilding to do.

Lumakras is the next test of FDA’s hardening stance

After Exkivity signals another accelerated approval slowdown the Amgen drug tomorrow faces an adcom over its own conditional approval.

What’s that, a win for CD47?

ALX Oncology claims the first ever success for a CD47 inhibitor in a global randomised solid tumour study.

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