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The menin fault lines emerge

With revumenib’s broader coverage Syndax tries to gain ground on Kura’s ziftomenib, but hits a new snag.

ESMO 2023 preview – Pluvicto splashes down among the late-breakers

Beyond lung cancer this year’s ESMO promises several other late-breaking datasets that could change clinical practice.

ESMO 2023 preview – J&J pulls a Mariposa rabbit out of the hat

And there won’t be a long to wait for the full data, with revelation that Mariposa features among numerous practice-changing late-breakers at ESMO.

A flurry of first-in-human trial initiations

Projects from Affini-T, Bolt, Chimeric and Alentis, all hitting novel targets, as well as one from A2 using an old one, are set for first clinical trial entry.

Another twist in Cardiff’s onvansertib plan

Front-line phase 3 plans take shape, as the company claims a new success, this time in pancreatic cancer.

Bridge mirrors Black Diamond and Blueprint’s search for something better

The companies have all switched to improved fourth-generation EGFR projects in lung cancer, a fact that likely shows how competitive this field has become.

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