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Approval milestones – Hutchmed, SpringWorks, Crispr and Ionis eye firsts

A work-stretched US FDA has several key approval application still to review by the end of 2023.

Astra works to avoid a datopotamab double dip

As Tropion-Breast01 is toplined positive Astra ensures the markets know that overall survival isn’t a washout.

Novartis goes 0 for 2 in PD-1 blockade

BeiGene regains rights to tislelizumab as another oncology asset blows up for Novartis.

12 years on, Jakafi faces serious JAK competition

Momelotinib gains full US approval in a broader setting than expected, validating GSK’s $1.9bn buyout of Sierra Oncology.

Bristol seeks novelty in TIGIT

Disclosure of BMS-986442’s second target antigen endorses Agenus, and is highly relevant for GSK and Compugen too.

AbbVie opt-out puts the focus on TeneoOne

The big pharma group had two anti-BCMA assets to choose from, and yesterday gave Harpoon the bad news.

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