Though lung cancer looks promising a partner is now needed.
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Deteriorating efficacy and a treatment-related death with Zynlonta plus Columvi spook investors.
Four more failed tiragolumab trials, including Imbrave-152, will feature.
The Chinese group will soon start a pivotal trial of its ADC ruza-can in first-line NSCLC.
While InxMed, Takara and L&L have phase 3 plans in lung cancer and beyond.
The company will be the first to take a FcRH5-targeting project into phase 3.
Like Orserdu, giredestrant works in all-comers in an ESR1m-enriched trial.
Big pharma interest remains, but the mood is fast turning gloomy.
