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Ascentage’s Venclexta challenge looks wildly optimistic

A just revealed clinical trial listing shows Ascentage’s BCL-2 inhibitor being compared against an outdated standard of care.

J&J speeds into new bladder cancer trial

The company takes another project from Taris into phase 3 as it chases a $5bn market.

FDA knocks back Regeneron’s CD20 T-cell engager

The decision highlights the fact that Regeneron is still doing dose-finding work for odronextamab.

Immutep approaches Lag3 crunch time

Results with eftilagimod alpha in first-line head and neck cancer threaten to cloud partnering prospects.

AbbVie begins its Steap1 climb

Other projects new to the clinic include Haisco’s USP1 inhibitor and and Avistone’s type II c-MET blocker.

Yervoy delivers a surprise in liver cancer

Checkmate-9DW scores a topline win on overall survival, when failure seemed more likely.

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