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Recent articles

Conjugates enter their first clinical trials

Two Kelun ADCs and two actinium-based radioconjugates start phase 1.

More bad vibes kill off Merck’s TIGIT and Lag3

Merck ditches vibostolimab and favezelimab following huge pivotal programmes.

Affimed needs more time with AFM24

Data deteriorate, leaving cash-strapped Affimed relying on a post-hoc analysis and higher dosing.

Bicycle has a wobble

Zelenectide looks uncompetitive versus Padcev in bladder cancer, while elsewhere a biomarker strategy beckons.

Another pan-KRAS project enters the clinic

Quanta now has a “G12V-preferring” multi-KRAS asset on its clinical roster.

SABCS 2024 – Lilly's PI3Kα push is no longer mutation-specific

Lilly sheds more light on its second PI3Kα take, as Relay's combo data improve.