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ESMO 2024 – Scorpion joins Relay in the alpha club

What Relay managed with a combo Scorpion might be able to do with STX-478 monotherapy.

ESMO 2024 – Astellas defends its degrader

Despite seeing dose-limiting toxicities, the group is going higher with its KRAS G12D project.

ESMO 2024 – Torl challenges BioNTech in Claudin6

Efficacy with Torl’s ADC looks in line, while toxicity with BNT211 still looms large.

ESMO 2024 – combos could be the way forward for CDK2

Incyte’s first substantial data with INCB123667 are eclipsed by Pfizer’s PF-07104091/atirmociclib combo.

ESMO 2024 – changing FDA stance could haunt Astra’s Niagara win

Niagara looks sound, but how much benefit did Imfinzi contribute to each of its two settings?

ESMO 2024 – Keytruda/Lenvima leap... up to a point

Leap-012 delivers a technical win, but filing might hinge on overall survival and a call on toxicity.

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