Celcuity goes early with its Pfizer cast-off
The company is to start a first-line phase 3 breast cancer trial of gedatolisib, as second-line data approach.
The company is to start a first-line phase 3 breast cancer trial of gedatolisib, as second-line data approach.
But the timeline for a US green light is less clear, and the group has a cash crisis.
Two masked bispecific antibodies, licensed for $100m, produce promising early data.
Olema will soon enter the clinic, and Pfizer could shortly be in phase 3.
But, like Merck two weeks ago, GSK has failed to hit overall survival.
Data deteriorate, leaving cash-strapped Affimed relying on a post-hoc analysis and higher dosing.
Merck ditches vibostolimab and favezelimab following huge pivotal programmes.