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No holding back Claudin

New phase 1 entrants include Claudin18.2-targeting ADCs from Astra and Bolt.

CDH17 becomes flavour of the month

Antibody-drug conjugates hitting this target abound.

Vepdegestrant’s promise narrows

Arvinas and Pfizer abandon first-line atirmociclib combo plans only disclosed in January.

FDA red and green lights: April 2025

April saw a checkpoint inhibitor bonanza for Bristol and Akeso.

AACR 2025 – a requiem for Roche's TIGIT

Survival in Skyscraper-01 deteriorated, and bore no relation to the Cityscape result.

AACR 2025 – BioNTech sees its first combo glimmers

A BNT327 and BNT325 combo shows promise in platinum-resistant ovarian cancer.