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  1. 5,000 patients later Roche scraps its TIGIT

    … cards since the molecule put up dismal phase 1 data at ASCO 2024 , so the main surprise will be what took Roche so … RG6614 USP1 inhibitor (ex KSQ) Disappointed in ph1 at ASCO 2024 RO7589831/ RG6457 Werner helicase …

    - 07/28/2025 - 17:18

  2. Sino takes out the rest of Merck’s partner

    … China ph1/2 in solid tumours (monotx & combos); data at ASCO 2024: 13% ORR (2/16) with monotx LM-168 …

    - 07/18/2025 - 13:28

  3. AbbVie's telisotuzumab conjugate take two

    … relapsed colorectal cancer, where first-in-human data at ASCO 2024 showed 2.4mg/kg or higher dose scoring a 38% ORR …

    - 09/09/2025 - 13:04

  4. AbbVie gets a cMet niche

    … 2nd-line+ solid tumours, incl CRC (+/- Avastin) Data at ASCO 2024 in CRC (>35% ORR in high cMet expressers at doses …

    - 05/19/2025 - 10:52

  5. Qilu nabs a new B7-H3 contender

    … In a Chinese phase 1/2 solid tumour trial reported at ASCO 2024, MHB088C produced a 61% overall response rate …

    - 05/13/2025 - 16:22

  6. Ivonescimab goes post-checkpoint

    … chemo; data due mid-2025 Chemo combo, vs chemo; data at ASCO 2024 2nd-line NSCLC (post PD-(L)1) (none) …

    - 04/17/2025 - 13:28

  7. Another false dawn for p53

    … presence KT-253* Kymera Ph1 data at ASCO 2024; Kymera no longer active in oncology …

    - 04/16/2025 - 10:14

  8. AACR 2025 preview – distressed biotechs seek redemption

    … CT038 Ph1 +/- toripalimab Had monoRx data at ASCO 2024 29 April clinical trials minisymposium …

    - 03/28/2025 - 08:55

  9. AACR 2025 preview – Roche's TIGIT postmortem

    … AffyImmune CT206 Ph1 thyroid cancers Had ASCO 2024 data   Merck had more success with …

    - 04/04/2025 - 13:32

  10. ELCC 2025 – AstraZeneca gets a survival boost from Laura

    … in stage III EGFRm NSCLC   ELCC 2025 ASCO 2024 Data maturity 31% 20% … HR=0.81; CI 0.42-1.56 Source: ELCC 2025 & ASCO 2024. Conferences Trial …

    - 03/26/2025 - 08:17