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Aegean in the clear

But Imfinzi's precise setting is uncertain, and big problems loom for companies pursuing similar trials.

Roche’s Skyscraper looks on shaky foundations

Roche curbs its TIGIT push, while a co-stimulation crunch could be bad news for Regeneron.

FDA sends a warning about perioperative cancer studies

An adcom on Imfinzi’s Aegean trial will show whether neoadjuvant and adjuvant benefits must be split out.

An unfamiliar name goes after familiar targets

Soon after filing to float in Hong Kong, Baili takes HER2 and DLL3-targeting ADCs into the clinic.

ESMO 2024 preview – Astellas unveils its KRAS degrader

ASP3082 grabs some early attention among degraders set to feature at ESMO.

ESMO 2024 preview – conjugates in the spotlight

Early attention falls on ADCs originated by ProfoundBio, SystImmune, MediLink and Seagen.

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