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ASCO 2025 – vepdegestrant matches rival degraders

Any hopes of differentiation could come down to side effects.

ASCO 2025 – Trodelvy heads for the front line

Gilead’s TROP2 ADC sets the bar for Astra/Daiichi’s Datroway in first-line TNBC.

ASCO 2025 – Dizal goes after the BTK leaders

DZD8586 shows some evidence that it can rescue BTK failures, but its precise role remains unclear.

ASCO 2025 – Exelixis’s son of Cabometyx improves

In first-line renal cancer, zanzalintinib plus Opdivo has outshone Cabometyx plus Opdivo.

ASCO 2025 – BioNTech’s latest Claudin6 effort falls short

BNT142 looks lacklustre, but the company still sees promise in mRNA-encoded bispecifics.

ASCO 2025 – 3SBio reveals what Pfizer got for its $1.25bn

Early data on SSGJ-707 in PD-L1-positive lung cancer spur comparisons against ivonescimab.