Moderna has also canned projects targeting KRAS and Ox40L/IL-23/IL-36γ.

Early data suggest that PD-(L)1 x VEGF bispecifics might challenge Keytruda in triple-negative disease.

The small cap biotech Instil Bio tries to follow in Summit’s slipstream.

So far ASP3082 looks no better than Jiangsu HengRui’s straight KRAS G12D inhibitor.

Having failed to get Zynyz approved in the second-line setting the group has the front line in its sights.

Data suggest a path forward for olomorasib plus Keytruda and chemo in PD-L1 low and negative patients.

The fortunes of RLY-2608 reverse, and a pivotal study will follow.